Nearby questions in Lexington Search Advanced Filters Search By Distance Within 5 miles Within 10 miles Within 15 miles Within 20 miles Within 25 miles Within 30 miles Within 35 miles Within 40 miles Within 45 miles Within 50 miles More Search Where is halfway between San Francisco and New York on the I-80? No Reviews Favorite The city of Lexington, Nebraska is approximately halfway between San Francisco and New York City on the I-80 at Exit 237. There are chain restaurants, hotels, gas stations and a Wal-Mart just off the highway. Read more...